No peptide is approved to treat insomnia. The best human sleep data belong to GHRH, the hormone sermorelin is cut from, which raised deep sleep in sleep-lab studies of 7 to 23 men. DSIP's best trial was negative. Ipamorelin, CJC-1295 and Selank have no sleep study at all.
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Sara Vance
Peptide research & literature
About
Sara writes the peptide guides, the mechanism explainers, and the research-literature reviews. Her background is in pharmacology research — eight years at a contract research organization running preclinical pharmacokinetics work before moving into science writing full-time. She reads the primary research literature so vialaudit readers don't have to, and she's the person on the desk who decides which peptide is mature enough for a guide. If a compound only has rodent data, she says so. If a Phase 2 trial is being misrepresented in community discussion, she writes the literature read. Sara writes under a pen name. The peptide research-protocol space attracts strong opinions and direct outreach to authors; she'd rather keep the email volume manageable and the work honest.
Topic specialty
Peptide guides, mechanism explainers, primary-literature reviews, pharmacokinetics summaries, dose-research literature, trial result reads.
Bibliography
A research read on the peptides currently studied for longevity outcomes - rapamycin, NAD+, MOTS-c, GHK-Cu, Klotho, epitalon, GHRH analogs, and the rest. Which have human evidence, which have only model-organism data, and what each actually does at the mechanism level.
KLOW is a four-component peptide stack growing fast in research-protocol discussion. Here's the literature read - what each compound does, what the mechanism overlap argues, and what's actually been studied as a combination.
The Wolverine stack is BPC-157 plus TB-500. No human trial has tested the pair. Of 81 blend lab results we checked, 1 failed on fill.
TRIUMPH-2 stepped retatrutide 2, 4, 6, 9, then 12 mg every 4 weeks. Week-by-week chart with syringe units for 10 and 20 mg vials.
Nausea hit 28% on 12 mg retatrutide vs 8% on placebo in TRIUMPH-2. Diarrhea, dysesthesia, hypotension and dropout rates by dose, from The Lancet.
All four retatrutide Phase 3 readouts on 12 mg: TRIUMPH-4 28.7% at 68 weeks (topline), TRIUMPH-1 25.0% (NEJM), TRIUMPH-2 18.8% (The Lancet), TRIUMPH-3 22.6% (topline).
Contact
Tips, corrections, or comments on research desk coverage: research@vialaudit.com