vialauditThe Roundup
MOTS-C·ILLINOIS·VERIFIED MAY 13, 2026

Is MOTS-c legal in Illinois?

CAVEATS APPLY

Investigational mitochondrial-derived peptide; no FDA approval; PCAC vote on 503A bulks scheduled July 23, 2026; WADA S2 class-based capture. No state-level peptide restrictions beyond federal law in Illinois.

CATEGORY · INVESTIGATIONAL

Full status breakdown

FEDERAL · STATE · SPORT-BODY

Federal status

FDA approval
investigational
DEA scheduling
not scheduled
503A compounding
Bulks list: under pcac review
Do-not-compound list: under pcac review
Scheduled for July 23, 2026 PCAC meeting (free base and acetate). Cannot be lawfully compounded under §503A.
PCAC review history
FDA Warning Letters
none on record for this compound
Shortage status
not currently on shortage list
Sale framing
Research-use-only posture: Same posture as other unapproved peptides — RUO label is not a safe harbor.
Personal possession: Not federally scheduled; possession is not a federal crime.

Illinois — state-specific

Sport-body status

WADA 2026
on prohibited list · class S2 · both
Captured by S2 class language and S0 (non-approved). Not specifically named.
USADA
NCAA

What we couldn’t verify

Also known as

3 ALIASES

MOTS-c is also marketed or referenced under the following names (vendor pseudonyms, brand names, chemical identifiers):

  • Mitochondrial Open Reading Frame 12S rRNA-c
  • MOTS-c acetate
  • CB4211 analogue

Related

FOLLOW-ONS

MOTS-c legality in other US states

State-by-state legal status for the same compound. Federal classification holds, state law varies.

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