vialauditThe Roundup
NAD+·US LEGAL STATUS·LAST CHECKED 12 OCT 2026

Is NAD+ legal?

Yes. NAD+ is sold as a dietary supplement in oral form, and pharmacies may compound it under FDA's interim policy. Injectable 'research' NAD+ sold for human use is an unapproved drug. It is not a controlled substance.

RESEARCH-LABELLED SALE
Oral supplement
PHARMACY COMPOUNDING
Allowed (Category 1)
PRESCRIPTION
No approved product
WADA 2026
Not listed

DESCRIBES THE LAW · NOT LEGAL ADVICE · NO DOSING INFORMATION

Federal, compounding and sport status

CHECKED 12 OCT 2026

Federal status

FDA approval
supplement category
DEA scheduling
not scheduled
503A compounding
FDA interim category: Category 1 (under evaluation; FDA does not intend to act against compliant pharmacies)
503A Bulks List: not on list
NAD is in Category 1 on FDA's 14 May 2026 categories list, so 503A pharmacies may compound it under the interim policy's conditions (registered source, valid COA). FDA proposed in 2019 not to add NAD to the Bulks List; that rule is not final, and NAD stays in Category 1 until it is.
FDA Warning Letters
  • May 6, 2020 — Alive By Nature, Inc. (cited: nad-plus, NMN) · LETTER ↗
Shortage status
not currently on shortage list
Sale framing
Research-use-only posture: NAD+ is widely sold as a dietary supplement (oral). Injectable/IV NAD+ in IV-bar/med-spa channels is in a different regulatory animal — FDA has flagged Category 2 status for compounded NAD+ injectable.
Personal possession: Oral dietary supplements are lawful. Possessing an injectable vial labeled for research could expose a buyer to nothing federally on possession alone, but the seller is at significant risk.

Sport-body status

WADA 2026
not prohibited
NAD+ is not listed. Separately, intravenous infusions or injections of more than 100 mL per 12-hour period are a prohibited method (M2.2) unless received in hospital or clinical settings.
USADA
not banned
NCAA
unknown

What we couldn’t verify

State rules

NONE FOUND

We found no state statute, board rule or enforcement action that names NAD+. The federal position above applies in all 50 states and DC.

What changed at the last check

1 CHANGES
DateFieldWasNowWhy
12 Oct 2026503A interim categoryCategory 2 (injectable)Category 1Corrected: FDA's 14 May 2026 categories list puts NAD in Category 1. It is not on the Category 2 safety-risk page. source ↗

Questions

3 ANSWERS
Is NAD+ legal in the US?

Yes. NAD+ is sold as a dietary supplement in oral form, and pharmacies may compound it under FDA's interim policy. Injectable 'research' NAD+ sold for human use is an unapproved drug. It is not a controlled substance.

Can a pharmacy compound NAD+?

NAD is in Category 1 on FDA's 14 May 2026 categories list, so 503A pharmacies may compound it under the interim policy's conditions (registered source, valid COA). FDA proposed in 2019 not to add NAD to the Bulks List; that rule is not final, and NAD stays in Category 1 until it is.

Is NAD+ banned in sport?

It is not on the WADA 2026 Prohibited List. NAD+ is not listed. Separately, intravenous infusions or injections of more than 100 mL per 12-hour period are a prohibited method (M2.2) unless received in hospital or clinical settings.

Sources

5 DOCUMENTS
  1. FDA approval record
  2. DEA controlled-substance schedules
  3. FDA 503A compounding position
  4. FDA warning letter to Alive By Nature, Inc., 6 May 2020
  5. WADA 2026 Prohibited List
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