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peptide comparison · metabolic × longevity

AOD-9604 vs MOTS-c

Two compounds, mechanism by mechanism. Where they overlap, where they don't, and which vendors stock each.

§ 01

Mechanism

aod-9604

AOD-9604

HGH Fragment 176-191Anti-Obesity Drug 9604

Synthetic 16-amino-acid fragment of human growth hormone (residues 176–191). Selectively retains the lipolytic effect of HGH while reducing growth-related effects.

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vs
mots-c

MOTS-c

Mitochondrial-Derived PeptideMOTS

Mitochondrial-derived peptide encoded in the 12S rRNA gene. Activates AMPK signaling and modulates metabolic adaptation. Often described as an exercise-mimetic compound.

Full guide →
§ 02

Key facts

factAOD-9604MOTS-c
category
·metaboliclongevity·
half-life
·~30 minutesNot fully characterized; multi-hour systemic effects observed·
research dosing
·Research literature cites 250–500 mcg daily subcutaneous, typically administered in the morning.Research literature cites 5–15 mg subcutaneous in cycles of 2–8 weeks.·
trending
search demand
50/10060/100
vendors stocking
·00·
aliases
·HGH Fragment 176-191 · Anti-Obesity Drug 9604Mitochondrial-Derived Peptide · MOTS·
§ 03

Use-case overlap

only aod-9604
  • fat metabolism research
  • lipolysis studies
  • HGH fragment research
both

none

only mots-c
  • mitochondrial function
  • exercise-response research
  • metabolic regulation
§ 04

Where to buy

aod-9604
AOD-9604
0 verified vendors
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mots-c
MOTS-c
0 verified vendors
See all vendors →
§ 05

Sources

  1. [01]AOD-9604 and obesity research — Obesity Reviews· AOD-9604
  2. [02]AOD-9604 Phase 2 trial results· AOD-9604
  3. [03]The mitochondrial-derived peptide MOTS-c regulates muscle metabolism — Cell Metabolism· MOTS-c
  4. [04]MOTS-c and mitochondrial communication — Trends in Endocrinology· MOTS-c
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