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peptide comparison · metabolic × growth

Cagrilintide vs Tesamorelin

Two compounds, mechanism by mechanism. Where they overlap, where they don't, and which vendors stock each.

§ 01

Mechanism

cagrilintide

Cagrilintide

AM833long-acting amylin analog

Synthetic long-acting amylin analog. Activates amylin and calcitonin receptors. Studied in combination with semaglutide as CagriSema in Phase 3 obesity trials.

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vs
tesamorelin

Tesamorelin

TH9507Egrifta

Synthetic 44-amino-acid analog of growth hormone-releasing hormone (GHRH). Stimulates pituitary release of endogenous growth hormone in a pulsatile manner.

Full guide →
§ 02

Key facts

factCagrilintideTesamorelin
category
·metabolicgrowth·
half-life
·~7 days~30 minutes (with sustained pituitary effect)·
research dosing
·Research literature cites 0.16–4.5 mg weekly subcutaneous in dose-escalation studies.Research literature cites 1–2 mg daily subcutaneous, typically administered before bed.·
trending
search demand
○55/10065/100●
vendors stocking
·00·
aliases
·AM833 · long-acting amylin analogTH9507 · Egrifta·
§ 03

Use-case overlap

only cagrilintide
  • weight management research
  • amylin-analog studies
  • GLP-1 combination protocols
both

none

only tesamorelin
  • visceral fat reduction
  • GHRH analog research
  • HIV-associated lipodystrophy (FDA-approved indication)
§ 04

Where to buy

cagrilintide
Cagrilintide
0 verified vendors
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tesamorelin
Tesamorelin
0 verified vendors
See all vendors →
§ 05

Sources

  1. [01]Cagrilintide and semaglutide combination — The Lancet· Cagrilintide
  2. [02]Novo Nordisk CagriSema Phase 3 program· Cagrilintide
  3. [03]Effects of tesamorelin on visceral adipose tissue — JAMA· Tesamorelin
  4. [04]FDA approval label — Egrifta· Tesamorelin
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