Is IGF-1 LR3 legal?
Not as a drug. IGF-1 LR3 has no FDA approval, so selling it for human use breaks federal drug law, and a 'research use only' label does not protect a seller whose site signals human use. It is not a controlled substance, and possessing it is not a federal crime. Pharmacies cannot compound it.
DESCRIBES THE LAW · NOT LEGAL ADVICE · NO DOSING INFORMATION
Federal, compounding and sport status
CHECKED 12 OCT 2026Federal status
Sport-body status
What we couldn’t verify
State rules
NONE FOUNDWe found no state statute, board rule or enforcement action that names IGF-1 LR3. The federal position above applies in all 50 states and DC.
What changed at the last check
1 CHANGES| Date | Field | Was | Now | Why |
|---|---|---|---|---|
| 12 Oct 2026 | WADA 2026 | prohibited (S2.1) | prohibited (S2.3) | Covered under S2.3: 'Insulin-like growth factor 1 (IGF-1, mecasermin) and its analogues'. source ↗ |
Questions
3 ANSWERSIs IGF-1 LR3 legal in the US?
Not as a drug. IGF-1 LR3 has no FDA approval, so selling it for human use breaks federal drug law, and a 'research use only' label does not protect a seller whose site signals human use. It is not a controlled substance, and possessing it is not a federal crime. Pharmacies cannot compound it.
Can a pharmacy compound IGF-1 LR3?
Not in any of FDA's 503A categories and not eligible. Distinct from mecasermin (Increlex), the approved recombinant IGF-1.
Is IGF-1 LR3 banned in sport?
Yes. It is prohibited at all times under WADA 2026 class S2.3. Covered under S2.3: 'Insulin-like growth factor 1 (IGF-1, mecasermin) and its analogues'.