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peptide comparison · metabolic

Cagrilintide vs Tirzepatide

Two compounds, mechanism by mechanism. Where they overlap, where they don't, and which vendors stock each.

§ 01

Mechanism

cagrilintide

Cagrilintide

AM833long-acting amylin analog

Synthetic long-acting amylin analog. Activates amylin and calcitonin receptors. Studied in combination with semaglutide as CagriSema in Phase 3 obesity trials.

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vs
tirzepatide

Tirzepatide

MounjaroZepbound

Dual GLP-1 / GIP receptor agonist. FDA-approved as Mounjaro (T2D) and Zepbound (obesity).

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§ 02

Key facts

factCagrilintideTirzepatide
category
·metabolicmetabolic·
half-life
·~7 days~5 days·
research dosing
·Research literature cites 0.16–4.5 mg weekly subcutaneous in dose-escalation studies.Research literature cites 2.5–15 mg weekly subcutaneous, escalated over 16+ weeks.·
trending
search demand
○55/10088/100●
vendors stocking
○07●
aliases
·AM833 · long-acting amylin analogMounjaro · Zepbound·
§ 03

Use-case overlap

only cagrilintide
  • weight management research
  • amylin-analog studies
  • GLP-1 combination protocols
both

none

only tirzepatide
  • weight loss
  • type 2 diabetes
§ 04

Where to buy

cagrilintide
Cagrilintide
0 verified vendors
See all vendors →
tirzepatide
Tirzepatide
7 verified vendors
Amino AsylumAscension PeptidesLimitless Life NootropicsParadigm Peptides+3 more
See all vendors →
§ 05

Sources

  1. [01]Cagrilintide and semaglutide combination — The Lancet· Cagrilintide
  2. [02]Novo Nordisk CagriSema Phase 3 program· Cagrilintide
  3. [03]Tirzepatide once weekly for the treatment of obesity (NEJM)· Tirzepatide
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