BPC-157 is a synthetic 15-amino-acid peptide derived from a fragment of body protection compound, a protein found in human gastric juice. It is studied in preclinical research for tendon recovery, gut healing, and soft-tissue injury, with proposed mechanisms including angiogenesis and anti-inflammatory pathways. Human clinical data is sparse; almost all published research is in rodent models.
Research notes
How does BPC-157 work?
BPC-157 is a 15-amino-acid synthetic peptide derived from a fragment of body protection compound, a protein found in human gastric juice. The exact mechanism remains under investigation, but preclinical research points to angiogenesis promotion and anti-inflammatory pathways as the primary effects.
What doses are used in research?
Most published research uses 250–500 mcg daily via subcutaneous injection in cycles of 4–8 weeks. Oral administration appears in some studies but bioavailability data is limited.
What it's researched for
- tendon recovery
- gut healing
- soft tissue injury
Where to source it
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Frequently asked about BPC-157
What is BPC-157?
BPC-157 is a 15-amino-acid synthetic peptide derived from a fragment of body protection compound, a protein found in human gastric juice. It is one of the most-studied peptides in the recovery and biohacker community, with most research focused on tendon, ligament, and gut-tissue repair.
How does BPC-157 work?
The exact mechanism is not fully characterized. Preclinical research points to two primary pathways: angiogenesis promotion (formation of new blood vessels at injury sites) and anti-inflammatory signaling. Most of the published evidence comes from rodent injury models rather than human clinical trials.
Is BPC-157 approved by the FDA?
No. BPC-157 is not FDA-approved for any human indication and is not on any country's approved-drug list. In late 2023 the FDA placed BPC-157 on its 503A bulks-list review with concerns about pharmacy compounding. It is sold only as research-grade material.
What doses are used in BPC-157 research?
Published research most often uses 250–500 mcg daily via subcutaneous injection in 4–8 week protocols. Oral administration appears in some studies but bioavailability data is limited. Doses cited here are research-protocol references, not human-use recommendations.
What is the typical purity of research-grade BPC-157?
Third-party Janoshik Analytical tests in our corpus typically show 97–99% purity by HPLC for BPC-157 from the vendors we audit. Per-vendor purity numbers, identity confirmations, and pass/fail status are listed in the vendor leaderboard further down this page.